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BB3 (IHC-grade), Bombesin Receptor 3 Antibody

Citations
Immunohistochemical identification of Bombesin receptor 3 in human ovarian carcinoma.
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  • 7TM0040N-IC
  • 100 µl
  • Rabbit
The BB3 receptor antibody is directed against the distal end of the carboxyl-terminal tail of... more

The BB3 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human Bombesin Receptor 3. It can be used to detect BB3 in formalin-fixed, paraffin-embedded tissue sections by immunohistochemistry.

  Alternative Names BB3, BRS3, Bombesin Receptor 3 IUPHAR Target ID... more

 

Alternative Names BB3, BRS3, Bombesin Receptor 3
IUPHAR Target ID  40
UniProt ID  P32247
Immunohistochemistry (IHC)
1:100
Immunocytochemistry (ICC) not tested
Species Reactivity   Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Immunogen A synthetic peptide with sequence EISVTSFTGCSVKQAEDRF corresponds to amino acids 381-399 of human BB3
Form  Liquid
Purification Antigen affinity chromatography
Storage buffer Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions short-term 4°C, long-term -20°C
Figure 1. Immunohistochemical identification of Bombesin receptor 3 in human ovarian... more

Figure 1. Immunohistochemical identification of Bombesin receptor 3 in human ovarian carcinoma. Sections were dewaxed, microwaved in citric acid, and incubated with anti-BB3 (Bombesin receptor 3) antibody (7TM0040N-IC) at a dilution of 1:100. Sections were then sequentially treated with biotinylated anti-rabbit IgG and avidin-biotin solution. Sections were then developed in 3,3-diaminobenzidine (DAB)-glucose oxidase and lightly counterstained with hematoxylin. Note, BB3 receptors were detected at the plasma membrane of nearly all cells in human ovarian carcinoma.

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