Immuno-Grade PACAP Receptor 1 Antibodies
The PACAP receptor 1 (PAC1) is the specific receptor for PACAP-27 and PACAP-38. PAC1 is coupled to Gs proteins. The PAC1 receptor may regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. In the spinal cord, PAC1 regulates the release of dynorphin. PAC1 activation causes smooth muscle relaxation and secretion in the gastrointestinal tract where it is expressed in myenteric neurons.