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GPR84 Receptor Antibodies

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Agonist-induced Threonine263/Threonine264 phosphorylation of GPR84
pT263/pT264-GPR84 (phospho-GPR84 Antibody)
Threonine263/Threonine264 (T263/T264) is major phosphorylation site of human GPR84 receptor. The pT263/pT264-GPR84 antibody detects phosphorylation in response to agonists. T263/T264 phosphorylation is likely to be involved in efficient...
$ 350.00
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Agonist-induced Serine221/Serine224 phosphorylation of GPR84
pS221/pS224-GPR84 (phospho-GPR84 Antibody)
Serine221/Serine224 (S221/S224) is major phosphorylation site of human GPR84 receptor. The pS221/pS224-GPR84 antibody detects phosphorylation in response to agonists. S221/S224 phosphorylation is likely to be involved in efficient ligand...
$ 350.00
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Validation of the G protein-coupled Receptor 84 in transfected HEK293 cells
GPR84 (non-phospho), G Protein-Coupled Receptor...
The GPR84 antibody is directed against the distal end of the carboxyl-terminal tail of human GRP84. It can be used to detect total GPR84 receptors in Western blots independent of phosphorylation. The GPR84 antibody can also be used to...
$ 350.00

GPR84 is a receptor for medium-chain free fatty acids with carbon chain lengths of C9 to C14. Capric acid C10, undecanoic acid C11 and lauric acid C12 are the most potent agonists. GPR84 is not activated by short-chain and long-chain saturated or unsaturated FFAs. Activation of GPR84 by medium-chain free fatty acid is coupled to a pertussis toxin sensitive Gi/o protein pathway. GPR84 may have important roles in processes from fatty acid metabolism and regulation of the immune system. GPR84 desensitization, β-arrestin recruitment and internalization are regulated by phosphorylation of 3rd intracellular loop threonine263/threonine264 (pT263/pT264-GPR84). This nomenclature refers to the human GPR84 receptor. For more information on GPR84 pharmacology please refer to the IUPHAR database. For further reading refer to:

Stoddart LA, Smith NJ, Milligan G. International Union of Pharmacology. LXXI. Free fatty acid receptors FFA1, -2, and -3: pharmacology and pathophysiological functions. Pharmacol Rev. 2008 Dec;60(4):405-17. doi: 10.1124/pr.108.00802. Epub 2008 Dec 1. PMID: 19047536.

Riddy DM, Delerive P, Summers RJ, Sexton PM, Langmead CJ. G Protein-Coupled Receptors Targeting Insulin Resistance, Obesity, and Type 2 Diabetes Mellitus. Pharmacol Rev. 2018 Jan;70(1):39-67. doi: 10.1124/pr.117.014373. PMID: 29233848.

GPR84 is a receptor for medium-chain free fatty acids with carbon chain lengths of C9 to C14. Capric acid C10, undecanoic acid C11 and lauric acid C12 are the most potent agonists. GPR84 is... read more »
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GPR84 Receptor Antibodies

GPR84 is a receptor for medium-chain free fatty acids with carbon chain lengths of C9 to C14. Capric acid C10, undecanoic acid C11 and lauric acid C12 are the most potent agonists. GPR84 is not activated by short-chain and long-chain saturated or unsaturated FFAs. Activation of GPR84 by medium-chain free fatty acid is coupled to a pertussis toxin sensitive Gi/o protein pathway. GPR84 may have important roles in processes from fatty acid metabolism and regulation of the immune system. GPR84 desensitization, β-arrestin recruitment and internalization are regulated by phosphorylation of 3rd intracellular loop threonine263/threonine264 (pT263/pT264-GPR84). This nomenclature refers to the human GPR84 receptor. For more information on GPR84 pharmacology please refer to the IUPHAR database. For further reading refer to:

Stoddart LA, Smith NJ, Milligan G. International Union of Pharmacology. LXXI. Free fatty acid receptors FFA1, -2, and -3: pharmacology and pathophysiological functions. Pharmacol Rev. 2008 Dec;60(4):405-17. doi: 10.1124/pr.108.00802. Epub 2008 Dec 1. PMID: 19047536.

Riddy DM, Delerive P, Summers RJ, Sexton PM, Langmead CJ. G Protein-Coupled Receptors Targeting Insulin Resistance, Obesity, and Type 2 Diabetes Mellitus. Pharmacol Rev. 2018 Jan;70(1):39-67. doi: 10.1124/pr.117.014373. PMID: 29233848.

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