CCR5 (GP-non-phospho) Chemokine Receptor 5 Antibody, Guinea Pig

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Validation of the CC Chemokine Receptor 5 in transfected HEK293 cells

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Order number: 7TM0062N-GP
Content: 100 µl
Host: Guinea Pig

The non-phospho-CCR5 receptor antibody is directed against the distal end of the... more

The non-phospho-CCR5 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human CCR5. It can be used to detect total CCR5 receptors in Western blots independent of phosphorylation. The CCR5 antibody can also be used to isolate and enrich CCR5 receptors from tissue lysates.

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Alternative Names CCR5, CKR5, Chemokine Receptor 5, Chemokine (C-C motif)... more

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Alternative Names	CCR5, CKR5, Chemokine Receptor 5, Chemokine (C-C motif) Receptor 5, MIP-1 alpha Receptor
IUPHAR Target ID	62
UniProt ID	P51681
Western Blot (WB)	1:1000
Immunocytochemistry (ICC)	-
Species Reactivity	Human
Host / Isotype	Guinea Pig / IgG
Class	Polyclonal
Immunogen	A synthetic peptide corresponding to c-terminal end of human CCR5.
Form	Liquid
Purification	Antigen affinity chromatography
Storage buffer	Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions	short-term 4°C, long-term -20°C

Figure 1. Validation of the CC Chemokine Receptor 5 in transfected HEK293 cells. Native... more

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Figure 1. Validation of the CC Chemokine Receptor 5 in transfected HEK293 cells. Native HEK293 cells (MOCK) or HEK293 cells stably expressing the CC Chemokine Receptor 5 (CCR5) were lysed and immunoblotted with the anti-CCR5 antibody (7TM0062N-GP) at a dilution of 1:1000.

Isaikina P, Petrovic I, Jakob RP, Sarma P, Ranjan A, Baruah M, Panwalkar V, Maier T, Shukla AK,... more

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Isaikina P, Petrovic I, Jakob RP, Sarma P, Ranjan A, Baruah M, Panwalkar V, Maier T, Shukla AK, Grzesiek S. A key GPCR phosphorylation motif discovered in
arrestin2⋅CCR5 phosphopeptide complexes. Mol Cell. 2023 Jun 15;83(12):2108-2121.e7. doi: 10.1016/j.molcel.2023.05.002. Epub 2023 May 26. PMID: 37244255.

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