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Immuno-Grade Apelin Receptor Antibodies

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Immunohistochemical identification of APLN Receptor in human pancreas
APLNR (IHC-grade), Apelin Receptor Antibody
The non-phospho-APLNR antibody is directed against the distal end of the carboxyl-terminal tail of human apelin receptor. It also detects APLNR in cultured cells and tissue sections by immunohistochemistry. It can be used to detect total...
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The apelin receptor (APLNR) responds to apelin, a 36 amino-acid peptide which is cleaved from a 77 amino-acid precursor peptide. Apelin-36, apelin-13 and [Pyr1]apelin-13 are the predominant endogenous ligands. A second family of peptides named Elabela/Toddler has discovered independently as endogenous ligands. The apelin receptor is coupled to inhibitory G-proteins. A number of physiological roles for the receptor have emerged, including regulation of cardiovascular function, fluid homeostasis, the adipoinsular axis, gastrointestinal and immunomodulatory functions. For more information on APLNR pharmacology please refer to the IUPHAR database. For further reading refer to:

Pitkin SL, Maguire JJ, Bonner TI, Davenport AP. International Union of Basic and Clinical Pharmacology. LXXIV. Apelin receptor nomenclature, distribution, pharmacology, and function. Pharmacol Rev. 2010 Sep;62(3):331-42. doi: 10.1124/pr.110.002949. Epub 2010 Jul 6. PMID: 20605969.

The apelin receptor (APLNR) responds to apelin, a 36 amino-acid peptide which is cleaved from a 77 amino-acid precursor peptide. Apelin-36, apelin-13 and [Pyr1]apelin-13 are the predominant... read more »
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Immuno-Grade Apelin Receptor Antibodies

The apelin receptor (APLNR) responds to apelin, a 36 amino-acid peptide which is cleaved from a 77 amino-acid precursor peptide. Apelin-36, apelin-13 and [Pyr1]apelin-13 are the predominant endogenous ligands. A second family of peptides named Elabela/Toddler has discovered independently as endogenous ligands. The apelin receptor is coupled to inhibitory G-proteins. A number of physiological roles for the receptor have emerged, including regulation of cardiovascular function, fluid homeostasis, the adipoinsular axis, gastrointestinal and immunomodulatory functions. For more information on APLNR pharmacology please refer to the IUPHAR database. For further reading refer to:

Pitkin SL, Maguire JJ, Bonner TI, Davenport AP. International Union of Basic and Clinical Pharmacology. LXXIV. Apelin receptor nomenclature, distribution, pharmacology, and function. Pharmacol Rev. 2010 Sep;62(3):331-42. doi: 10.1124/pr.110.002949. Epub 2010 Jul 6. PMID: 20605969.

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