Premium Phosphosite-Specific 7TM Antibodies
Novel Tools for Your GPCR Research
Select Your Country of Delivery below

Tachykinin Receptor Phosphorylation Assays

Tachykinin receptors are activated by the endogenous peptides substance P (SP), neurokinin A (NKA), neurokinin B (NKB). There are three tachykinin receptors; NK1, NK2, and NK3, and each has a preferred ligand; SP, NKA, and NKB, respectively. The term tachykinin was originally used to identify SP because it produced spasmodic effects in various intestinal smooth muscle cells. Tachy is Greek for rapid and Kinin is Greek for set in motion. Together these terms described the rapid contraction of smooth muscle treated with SP. NK1 and NK3 are widely distributed in the central nervous system, while NK2 is localized in the smooth muscle of the gastrointestinal, respiratory, and urinary tracts and some discrete regions of the CNS such as the prefrontal cortex and the hippocampus. Antagonists such as aprepitant and fosaprepitant were approved for the prevention of nausea and vomiting associated with cancer chemotherapy.

Close filters
No results were found for the filter!
NEW
OD signals in pT356/pT357-NK1 Phosphorylation Assay
pT356/pT357-NK1 Phosphorylation Assay Kit
The pT356/pT357-NK1 Phosphorylation Assay Kit allows determination of NK1 Phosphorylation in 96-well plates without the need for Western blot analysis.
$ 600.00 *
NEW
OD signals in pS338/pT339-NK1 Phosphorylation Assay
pS338/pT339-NK1 Phosphorylation Assay Kit
The pS338/pT339-NK1 Phosphorylation Assay Kit allows determination of NK1 Phosphorylation in 96-well plates without the need for Western blot analysis.
$ 600.00 *
NEW
OD signals in pT344/pS347-NK1 Phosphorylation Assay
pT344/pS347-NK1 Phosphorylation Assay Kit
The pT344/pS347-NK1 Phosphorylation Assay Kit allows determination of NK1 Phosphorylation in 96-well plates without the need for Western blot analysis.
$ 600.00 *

For more information on chemokine receptor pharmacology please refer to the IUPHAR database. For further reading refer to:

Barrett J, Canning B, Coulson J, Dombrowsky E, Douglas SD, Fong TM, Heyward CY, Leeman SE, Remeshwar P. Tachykinin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database. IUPHAR/BPS Guide to Pharmacology CITE. 2019; 2019(4).

For more information on chemokine receptor pharmacology please refer to the  IUPHAR  database. For further reading refer to: Barrett J, Canning B, Coulson J, Dombrowsky E, Douglas... read more »
Close window
Tachykinin Receptor Phosphorylation Assays

For more information on chemokine receptor pharmacology please refer to the IUPHAR database. For further reading refer to:

Barrett J, Canning B, Coulson J, Dombrowsky E, Douglas SD, Fong TM, Heyward CY, Leeman SE, Remeshwar P. Tachykinin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database. IUPHAR/BPS Guide to Pharmacology CITE. 2019; 2019(4).

Recently viewed