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Tachykinin Receptor Antibodies

Tachykinin receptors are activated by the endogenous peptides substance P (SP), neurokinin A (NKA), neurokinin B (NKB). There are three tachykinin receptors; NK1, NK2, and NK3, and each has a preferred ligand; SP, NKA, and NKB, respectively. The term tachykinin was originally used to identify SP because it produced spasmodic effects in various intestinal smooth muscle cells. Tachy is Greek for rapid and Kinin is Greek for set in motion. Together these terms described the rapid contraction of smooth muscle treated with SP. NK1 and NK3 are widely distributed in the central nervous system, while NK2 is localized in the smooth muscle of the gastrointestinal, respiratory, and urinary tracts and some discrete regions of the CNS such as the prefrontal cortex and the hippocampus. Antagonists such as aprepitant and fosaprepitant were approved for the prevention of nausea and vomiting associated with cancer chemotherapy.

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pS338/pT339-NK1 Phosphorylation Assay Kit
pS338/pT339-NK1 Phosphorylation Assay Kit
The pT370-MOP Phosphorylation Assay Kit allows determination of MOP Phosphorylation in 96-well plates without the need for Western blot analysis.
$ 300.00 $ 600.00 *
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pT356/pT357-NK1 Phosphorylation Assay Kit
pT356/pT357-NK1 Phosphorylation Assay Kit
The pT370-MOP Phosphorylation Assay Kit allows determination of MOP Phosphorylation in 96-well plates without the need for Western blot analysis.
$ 300.00 $ 600.00 *
50
NEW
pT344/pS347-NK1 Phosphorylation Assay Kit
pT344/pS347-NK1 Phosphorylation Assay Kit
The pT370-MOP Phosphorylation Assay Kit allows determination of MOP Phosphorylation in 96-well plates without the need for Western blot analysis.
$ 300.00 $ 600.00 *

For more information on chemokine receptor pharmacology please refer to the IUPHAR database. For further reading refer to:

Barrett J, Canning B, Coulson J, Dombrowsky E, Douglas SD, Fong TM, Heyward CY, Leeman SE, Remeshwar P. Tachykinin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database. IUPHAR/BPS Guide to Pharmacology CITE. 2019; 2019(4).

For more information on chemokine receptor pharmacology please refer to the  IUPHAR  database. For further reading refer to: Barrett J, Canning B, Coulson J, Dombrowsky E, Douglas... read more »
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Tachykinin Receptor Antibodies

For more information on chemokine receptor pharmacology please refer to the IUPHAR database. For further reading refer to:

Barrett J, Canning B, Coulson J, Dombrowsky E, Douglas SD, Fong TM, Heyward CY, Leeman SE, Remeshwar P. Tachykinin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database. IUPHAR/BPS Guide to Pharmacology CITE. 2019; 2019(4).

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