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Cholecystokinin Receptor 2 Antibodies

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pT427/pS429-CCK2 (phospho-Cholecystokinin Receptor 2 Antibody)
pT427/pS429-CCK2 (phospho-Cholecystokinin...
Threonine427/Serine429 (T427/S429) is a major phosphorylation site of the CCK2 receptor. The pT427/pS429-CCK2 antibody detects phosphorylation in response to high-efficacy agonists. T427/S429 phosphorylation is a key regulator of CRF1...
$ 375.00 *
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pS437/pT439-CCK2 (phospho-Cholecystokinin Receptor 2 Antibody)
pS437/pT439-CCK2 (phospho-Cholecystokinin...
Serine437/Threonine439 (S437/T439) is a major phosphorylation site of the CCK2 receptor. The pS437/pT439-CCK2 antibody detects phosphorylation in response to high-efficacy agonists. S437/T439 phosphorylation is a key regulator of CCK2...
$ 375.00 *
Citations
 Validation of the Cholecystokinin Receptor 2 in transfected HEK293 cells
CCK2 (non-phospho), Cholecystokinin Receptor 2...
The CCK2 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human Cholecystokinin Receptor 2 (previously called CCKB). It can be used to detect total CCK2 receptors in Western blots independent of...
$ 300.00 *

The human cholcystokinin receptor 2 (CCK2) is activated by endogenous gastrin and cholecystokinin peptides. CCK2 receptor desensitization, β-arrestin recruitment and internalization are regulated by phosphorylation of carboxyl-terminal threonine427/serine429 (pT427/pS429-CCK2) and serine437/threonine439 (pS437/pT439-CCK2). This nomenclature refers to the human CCK2. This phosphorylation motif is conserved across species but corresponds to pT433/pS435-CCK2 and pS443/pT445-CCK2 in mice and pT432/pS434-CCK2 and pS442/pT444-CCK2 in rats. For more information on CCK2 pharmacology please refer to the IUPHAR database. For further reading refer to:

Noble F, Wank SA, Crawley JN, Bradwejn J, Seroogy KB, Hamon M, Roques BP. International Union of Pharmacology. XXI. Structure, distribution, and functions of cholecystokinin receptors. Pharmacol Rev. 1999 Dec;51(4):745-81. Erratum in: Pharmacol Rev 2000 Mar;52(1):177. PMID: 10581329.

Dufresne M, Seva C, Fourmy D. Cholecystokinin and gastrin receptors. Physiol Rev. 2006 Jul;86(3):805-47. doi: 10.1152/physrev.00014.2005. PMID: 16816139.

The human cholcystokinin receptor 2 ( CCK2 ) is activated by endogenous gastrin and cholecystokinin peptides. CCK2 receptor desensitization, β-arrestin recruitment and internalization are... read more »
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Cholecystokinin Receptor 2 Antibodies

The human cholcystokinin receptor 2 (CCK2) is activated by endogenous gastrin and cholecystokinin peptides. CCK2 receptor desensitization, β-arrestin recruitment and internalization are regulated by phosphorylation of carboxyl-terminal threonine427/serine429 (pT427/pS429-CCK2) and serine437/threonine439 (pS437/pT439-CCK2). This nomenclature refers to the human CCK2. This phosphorylation motif is conserved across species but corresponds to pT433/pS435-CCK2 and pS443/pT445-CCK2 in mice and pT432/pS434-CCK2 and pS442/pT444-CCK2 in rats. For more information on CCK2 pharmacology please refer to the IUPHAR database. For further reading refer to:

Noble F, Wank SA, Crawley JN, Bradwejn J, Seroogy KB, Hamon M, Roques BP. International Union of Pharmacology. XXI. Structure, distribution, and functions of cholecystokinin receptors. Pharmacol Rev. 1999 Dec;51(4):745-81. Erratum in: Pharmacol Rev 2000 Mar;52(1):177. PMID: 10581329.

Dufresne M, Seva C, Fourmy D. Cholecystokinin and gastrin receptors. Physiol Rev. 2006 Jul;86(3):805-47. doi: 10.1152/physrev.00014.2005. PMID: 16816139.

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