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Chemerin Receptor 2 Antibodies

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Agonist-induced Serine331/Serine333 phosphorylation of Chemerin Receptor 2
pS331/pS333-CMKLR2 (phospho-Chemerin Receptor 2...
Serine331/Serine333 (S331/S333) is a major phosphorylation site of the Chemerin receptor 2 (CMKLR2). The pS331/pS333-CMKLR2 antibody detects phosphorylation in response to high-efficacy agonists. S331/S333 phosphorylation is a key...
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Agonist-induced Threonine335/Serine337 phosphorylation of Chemerin Receptor 2
pT335/pS337-CMKLR2 (phospho-Chemerin Receptor 2...
Threonine335/Serine337 (T335/S337) is a major phosphorylation site of the Chemerin receptor 2 (CMKLR2). The pT335/pS337-CMKLR2 antibody detects phosphorylation in response to high-efficacy agonists. T335/S337 phosphorylation is a key...
$ 375.00 *
Details
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Agonist-induced Serine343/Threonine345 phosphorylation of Chemerin Receptor 2
pS343/pT345-CMKLR2 (phospho-Chemerin Receptor 2...
Serine343/Threonine345 (S343/T345) is a major phosphorylation site of the Chemerin receptor 2 (CMKLR2). The pS343/pT345-CMKLR2 antibody detects phosphorylation in response to high-efficacy agonists. S343/T345 phosphorylation is a key...
$ 375.00 *
Details

Chemerin2 receptor (CMKLR2) is the second member of the chemerin family. The chemoattractant protein and adipokine, chemerin, is the endogenous ligand for both chemerin receptors. When GPR1 was de-orphanised it was re-named Chemerin2. The Chemerin2 receptor is regulated by phosphorylation of carboxyl-terminal serine331/serine333 (pS331/pS333-CMKLR2), threonine335/serine337 (pT335/pS337-CMKLR2) and serine343/threonine345 (pS343/pT345-CMKLR2). This nomenclature refers to the human CMKLR2. This phosphorylation motif is highly conserved across species and nearly identical in mice, rats and humans. For more information on CMKLR2 pharmacology please refer to the IUPHAR database. For further reading refer to:

Kennedy AJ, Davenport AP. International Union of Basic and Clinical Pharmacology CIII: Chemerin Receptors CMKLR1 (Chemerin1) and GPR1 (Chemerin2) Nomenclature, Pharmacology, and Function. Pharmacol Rev. 2018 Jan;70(1):174-196. doi: 10.1124/pr.116.013177. Epub 2017 Dec 26. PMID: 29279348

Davenport AP, Monaghan AE. Chemerin receptors (version 2019.3) in the IUPHAR/BPS Guide to Pharmacology Database. IUPHAR/BPS Guide to Pharmacology CITE. 2019; 2019(3). Available from: https://doi.org/10.2218/gtopdb/F338/2021.3.

Chemerin2 receptor (CMKLR2) is the second member of the chemerin family. The chemoattractant protein and adipokine, chemerin, is the endogenous ligand for both chemerin receptors. When GPR1... read more »
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Chemerin Receptor 2 Antibodies

Chemerin2 receptor (CMKLR2) is the second member of the chemerin family. The chemoattractant protein and adipokine, chemerin, is the endogenous ligand for both chemerin receptors. When GPR1 was de-orphanised it was re-named Chemerin2. The Chemerin2 receptor is regulated by phosphorylation of carboxyl-terminal serine331/serine333 (pS331/pS333-CMKLR2), threonine335/serine337 (pT335/pS337-CMKLR2) and serine343/threonine345 (pS343/pT345-CMKLR2). This nomenclature refers to the human CMKLR2. This phosphorylation motif is highly conserved across species and nearly identical in mice, rats and humans. For more information on CMKLR2 pharmacology please refer to the IUPHAR database. For further reading refer to:

Kennedy AJ, Davenport AP. International Union of Basic and Clinical Pharmacology CIII: Chemerin Receptors CMKLR1 (Chemerin1) and GPR1 (Chemerin2) Nomenclature, Pharmacology, and Function. Pharmacol Rev. 2018 Jan;70(1):174-196. doi: 10.1124/pr.116.013177. Epub 2017 Dec 26. PMID: 29279348

Davenport AP, Monaghan AE. Chemerin receptors (version 2019.3) in the IUPHAR/BPS Guide to Pharmacology Database. IUPHAR/BPS Guide to Pharmacology CITE. 2019; 2019(3). Available from: https://doi.org/10.2218/gtopdb/F338/2021.3.

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