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Neuropeptide FF Receptor Antibodies

The Neuropeptide FF receptor family contains two subtypes, NPFF1 and NPFF2, which exhibit high affinities for neuropeptide FF (NPFF) and RFamide related peptides (RFRP). The NPFF1 receptor is broadly distributed in the central nervous system with the highest levels found in the limbic system and the hypothalamus. The NPFF2 receptor is present in high density in the superficial layers of the mammalian spinal cord where it is involved in nociception and modulation of opioid functions. Both NPFF1 and NPFF2 couple to inhibitory G proteins.

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Agonist-induced Serine361 phosphorylation of the Neuropeptide FF Receptor 1
pS361-NPFF1 (phospho-Neuropeptide FF Receptor 1...
Serine361 (S361) is major phosphorylation site of the Neuropeptide FF Receptor 1 (NPFF1). The pS361-NPFF1 antibody detects phosphorylation in response to agonists. S361 phosphorylation is likely to be involved in efficient ligand...
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For more information on neuropeptide FF receptor pharmacology please refer to the IUPHAR database. For further reading refer to:

Mollereau-Manaute C, Moulédous L, Roumy M, Tsutsui K, Ubuka T, Zajac JM. Neuropeptide FF/neuropeptide AF receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database. IUPHAR/BPS Guide to Pharmacology CITE. 2019; 2019(4). Available from: https://doi.org/10.2218/gtopdb/F43/2019.4.

For more information on neuropeptide FF receptor pharmacology please refer to the  IUPHAR  database. For further reading refer to: Mollereau-Manaute C, Moulédous L, Roumy M,... read more »
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Neuropeptide FF Receptor Antibodies

For more information on neuropeptide FF receptor pharmacology please refer to the IUPHAR database. For further reading refer to:

Mollereau-Manaute C, Moulédous L, Roumy M, Tsutsui K, Ubuka T, Zajac JM. Neuropeptide FF/neuropeptide AF receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database. IUPHAR/BPS Guide to Pharmacology CITE. 2019; 2019(4). Available from: https://doi.org/10.2218/gtopdb/F43/2019.4.

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