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CXC Chemokine Receptor 3 Antibodies

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Agonist-induced Serine358/Threonine360/Serine361 phosphorylation of the CXC Chemokine Receptor 3
pS358/pT360/pS361-CXCR3 (phospho-CXC Chemokine...
Serine358/Threonine360/Serine361 (S358/T360/S361) are a major phosphorylation sites of the CXCR3 receptor. The pS358/pT360/pS361-CXCR3 detects phosphorylation in response to high- and low-efficacy agonists. S358/T360/S361 phosphorylation...
$ 375.00 *
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Validation of the CXCR3 Receptor in transfected HEK293 cells.
CXCR3 (non-phospho), CXCR3 Chemokine Receptor...
The non-phospho-CXCR3 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human CXCR3. It can be used to detect total CXCR3 receptors in Western blots independent of phosphorylation.
$ 375.00 *
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CXCR3 is the receptor for the C-X-C chemokines CXCL9, CXCL10 and CXCL11. It mediates the proliferation, survival and angiogenic activity of human mesangial cells through a heterotrimeric G-protein signaling pathway. CXCR3 receptor desensitization, β-arrestin recruitment and internalization are regulated by phosphorylation of carboxyl-terminal serine358, threonine360, serine361 (pS358/pT360/ps361-CXCR3). This nomenclature refers to the human CXCR3 but is conserved in mice and rats. For more information on CXCR3 pharmacology please refer to the IUPHAR database. For further reading refer to:

Bachelerie F, Ben-Baruch A, Burkhardt AM, Combadiere C, Farber JM, Graham GJ, Horuk R, Sparre-Ulrich AH, Locati M, Luster AD, Mantovani A, Matsushima K, Murphy PM, Nibbs R, Nomiyama H, Power CA, Proudfoot AE, Rosenkilde MM, Rot A, Sozzani S, Thelen M, Yoshie O, Zlotnik A. International Union of Basic and Clinical Pharmacology. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors. Pharmacol Rev. 2013 Nov 11;66(1):1-79. doi: 10.1124/pr.113.007724. Print 2014. Review. Erratum in: Pharmacol Rev. 2014 Apr;66(2):467. PubMed PMID: 24218476; PubMed Central PMCID: PMC3880466.

  CXCR3 is the receptor for the C-X-C chemokines CXCL9, CXCL10 and CXCL11. It mediates the proliferation, survival and angiogenic activity of human mesangial cells through a heterotrimeric... read more »
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CXC Chemokine Receptor 3 Antibodies

 

CXCR3 is the receptor for the C-X-C chemokines CXCL9, CXCL10 and CXCL11. It mediates the proliferation, survival and angiogenic activity of human mesangial cells through a heterotrimeric G-protein signaling pathway. CXCR3 receptor desensitization, β-arrestin recruitment and internalization are regulated by phosphorylation of carboxyl-terminal serine358, threonine360, serine361 (pS358/pT360/ps361-CXCR3). This nomenclature refers to the human CXCR3 but is conserved in mice and rats. For more information on CXCR3 pharmacology please refer to the IUPHAR database. For further reading refer to:

Bachelerie F, Ben-Baruch A, Burkhardt AM, Combadiere C, Farber JM, Graham GJ, Horuk R, Sparre-Ulrich AH, Locati M, Luster AD, Mantovani A, Matsushima K, Murphy PM, Nibbs R, Nomiyama H, Power CA, Proudfoot AE, Rosenkilde MM, Rot A, Sozzani S, Thelen M, Yoshie O, Zlotnik A. International Union of Basic and Clinical Pharmacology. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors. Pharmacol Rev. 2013 Nov 11;66(1):1-79. doi: 10.1124/pr.113.007724. Print 2014. Review. Erratum in: Pharmacol Rev. 2014 Apr;66(2):467. PubMed PMID: 24218476; PubMed Central PMCID: PMC3880466.

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