Immuno-Grade Cholecystokinin Receptor 1 Antibodies
The cholecystokinin receptor 1 (CCK1) is the specific receptor for cholecystokinin-8 but not for gastrin. CCK1 regulates multiple functions in the gastrointestinal tract including gastric acid secretion, gastric emptying, and gall bladder motility. CCK1 is highly abundant in chief cells of the gastric mucosa, in myenteric ganglion cells, and in myenteric nerve fibers. CCK1 receptors are also expressed at the plasma membrane of human tumors including carcinoids, insulinomas, pituitary adenomas and meningiomas.