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Immuno-Grade GPR17 Receptor Antibodies

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Immunohistochemical identification of G Protein-coupled Receptor 17 in oligodendrocytes.
GPR17 (IHC-grade), G Protein-Coupled Receptor...
The GPR17 antibody is directed against the distal end of the carboxyl-terminal tail of mouse, rat and human GRP17. It can be used to detect total GPR17 receptors in Western blots independent of phosphorylation. The GPR17 antibody can...
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GPR17 is an orphan GPCR. The endogenous ligand for GPR17 remains to be discovered. GPR17 has previously been reported to be a dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). GPR17 may mediate brain damage by nucleotides and CysLTs following ischemia. In the central nervous system, GPR17 is expressed in a subset of (pre)-oligodendrocytes and in neurogenic areas. After spinal cord injury, or focal cerebral ischaemia, GPR17 expression is induced in a population of proliferating microglial cells in the lesioned area.

GPR17 is an orphan GPCR. The endogenous ligand for GPR17 remains to be discovered. GPR17 has previously been reported to be a dual specificity receptor for uracil nucleotides and cysteinyl... read more »
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Immuno-Grade GPR17 Receptor Antibodies

GPR17 is an orphan GPCR. The endogenous ligand for GPR17 remains to be discovered. GPR17 has previously been reported to be a dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). GPR17 may mediate brain damage by nucleotides and CysLTs following ischemia. In the central nervous system, GPR17 is expressed in a subset of (pre)-oligodendrocytes and in neurogenic areas. After spinal cord injury, or focal cerebral ischaemia, GPR17 expression is induced in a population of proliferating microglial cells in the lesioned area.

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