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Chemerin Receptor Antibodies

The chemoattractant protein and adipokine, chemerin, has been shown to be the endogenous ligand for both chemerin family receptors. Chemerin 1 receptor was the founding family member, and when GPR1 was de-orphanised it was re-named Chemerin 2 receptor. Chemerin1 is also activated by the lipid-derived, anti-inflammatory ligand resolvin E1 (RvE1), which is formed via the sequential metabolism of EPA by aspirin-modified cyclooxygenase and lipoxygenase. In addition, two GPCRs for resolvin D1 (RvD1) have been identified: FPR2/ALX, the lipoxin A4 receptor, and GPR32, an orphan receptor.

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Agonist-induced Serine345/Serine346 phosphorylation of Chemerin Receptor 1
pS345/pS346-CMKLR1 (phospho-Chemerin Receptor 1...
Serine345/Serine346 (S345/S346) is a major phosphorylation site of the Chemerin receptor 1 (CMKLR1). The pS345/pS346-CMKLR1 antibody detects phosphorylation in response to high-efficacy agonists. S345/S346 phosphorylation is a key...
$ 375.00 *
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NEW
Agonist-induced Serine352/Threonine354 phosphorylation of Chemerin Receptor 1
pS352/pT354-CMKLR1 (phospho-Chemerin Receptor 1...
Serine352/Threonine354 (S352/T354) is a major phosphorylation site of the Chemerin receptor 1 (CMKLR1). The pS352/pT354-CMKLR1 antibody detects phosphorylation in response to high-efficacy agonists. S352/T354 phosphorylation is a key...
$ 375.00 *
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NEW
Agonist-induced Serine357/Serine358 phosphorylation of Chemerin Receptor 1.
pS357/pS358-CMKLR1 (phospho-Chemerin Receptor 1...
Serine357/Serine358 (S357/S358) is a major phosphorylation site of the Chemerin receptor 1 (CMKLR1). The pS357/pS358-CMKLR1 antibody detects phosphorylation in response to high-efficacy agonists. S357/S358 phosphorylation is a key...
$ 375.00 *
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NEW
Agonist-induced Serine331/Serine333 phosphorylation of Chemerin Receptor 2
pS331/pS333-CMKLR2 (phospho-Chemerin Receptor 2...
Serine331/Serine333 (S331/S333) is a major phosphorylation site of the Chemerin receptor 2 (CMKLR2). The pS331/pS333-CMKLR2 antibody detects phosphorylation in response to high-efficacy agonists. S331/S333 phosphorylation is a key...
$ 375.00 *
Details
NEW
Agonist-induced Threonine335/Serine337 phosphorylation of Chemerin Receptor 2
pT335/pS337-CMKLR2 (phospho-Chemerin Receptor 2...
Threonine335/Serine337 (T335/S337) is a major phosphorylation site of the Chemerin receptor 2 (CMKLR2). The pT335/pS337-CMKLR2 antibody detects phosphorylation in response to high-efficacy agonists. T335/S337 phosphorylation is a key...
$ 375.00 *
Details
NEW
Agonist-induced Serine343/Threonine345 phosphorylation of Chemerin Receptor 2
pS343/pT345-CMKLR2 (phospho-Chemerin Receptor 2...
Serine343/Threonine345 (S343/T345) is a major phosphorylation site of the Chemerin receptor 2 (CMKLR2). The pS343/pT345-CMKLR2 antibody detects phosphorylation in response to high-efficacy agonists. S343/T345 phosphorylation is a key...
$ 375.00 *
Details

For more information on chemokine receptor pharmacology please refer to the IUPHAR database. For further reading refer to:

Kennedy AJ, Davenport AP. International Union of Basic and Clinical Pharmacology CIII: Chemerin Receptors CMKLR1 (Chemerin1) and GPR1 (Chemerin2) Nomenclature, Pharmacology, and Function. Pharmacol Rev. 2018 Jan;70(1):174-196. doi: 10.1124/pr.116.013177. Epub 2017 Dec 26. PMID: 29279348

Davenport AP, Monaghan AE. Chemerin receptors (version 2019.3) in the IUPHAR/BPS Guide to Pharmacology Database. IUPHAR/BPS Guide to Pharmacology CITE. 2019; 2019(3). Available from: https://doi.org/10.2218/gtopdb/F338/2021.3.

For more information on chemokine receptor pharmacology please refer to the  IUPHAR  database. For further reading refer to: Kennedy AJ, Davenport AP. International Union of Basic... read more »
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Chemerin Receptor Antibodies

For more information on chemokine receptor pharmacology please refer to the IUPHAR database. For further reading refer to:

Kennedy AJ, Davenport AP. International Union of Basic and Clinical Pharmacology CIII: Chemerin Receptors CMKLR1 (Chemerin1) and GPR1 (Chemerin2) Nomenclature, Pharmacology, and Function. Pharmacol Rev. 2018 Jan;70(1):174-196. doi: 10.1124/pr.116.013177. Epub 2017 Dec 26. PMID: 29279348

Davenport AP, Monaghan AE. Chemerin receptors (version 2019.3) in the IUPHAR/BPS Guide to Pharmacology Database. IUPHAR/BPS Guide to Pharmacology CITE. 2019; 2019(3). Available from: https://doi.org/10.2218/gtopdb/F338/2021.3.

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