Premium Phosphosite-Specific 7TM Antibodies
Novel Tools for Your GPCR Research
Select Your Country of Delivery below

Immuno-Grade Corticotropin-Releasing Factor Receptor 1 Antibodies

Close filters
No results were found for the filter!
Citations
KO-Validated
Immunohistochemical identification of Corticotropin-Releasing Factor Receptor 1 in anterior pituitary
CRF1 (IHC-grade), Corticotropin-Releasing...
The CRF1 receptor antibody is directed against the distal part of the carboxyl-terminal tail of human CRF1. It can be used to detect total CRF1 receptors in Western blots independent of phosphorylation. The CRF1 antibody can also be used...
$ 375.00 *
Details

The human CRF1 receptor is widely expressed in the central nervous system with high levels of expression in cortex, cerebellum, hippocampus, basolateral amygdala, bed nucleus of the stria terminalis, olfactory bulb and anterior pituitary. In the periphery, CRF1 receptor is expressed at low levels in the skin, ovary, testis and adrenal gland. CRF, urocortin 1 (UCN1) and urotensin I all bind with high affinity to the mammalian CRF1 receptor and activate the cyclic AMP signaling pathway. In contrast, UCN2 and UCN3 do not bind to or activate CRF1 receptors. Therefore, CRF and urocortin 1 can be classified as the endogenous ligands for mammalian CRF1 receptors.

The human CRF1 receptor is widely expressed in the central nervous system with high levels of expression in cortex, cerebellum, hippocampus, basolateral amygdala, bed nucleus of the stria... read more »
Close window
Immuno-Grade Corticotropin-Releasing Factor Receptor 1 Antibodies

The human CRF1 receptor is widely expressed in the central nervous system with high levels of expression in cortex, cerebellum, hippocampus, basolateral amygdala, bed nucleus of the stria terminalis, olfactory bulb and anterior pituitary. In the periphery, CRF1 receptor is expressed at low levels in the skin, ovary, testis and adrenal gland. CRF, urocortin 1 (UCN1) and urotensin I all bind with high affinity to the mammalian CRF1 receptor and activate the cyclic AMP signaling pathway. In contrast, UCN2 and UCN3 do not bind to or activate CRF1 receptors. Therefore, CRF and urocortin 1 can be classified as the endogenous ligands for mammalian CRF1 receptors.

Recently viewed