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CC Chemokine Receptor 10 Antibodies

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Agonist-induced Threonine355 phosphorylation of the Chemokine Receptor 10
pT355-CCR10 (phospho-Chemokine Receptor 10...
Threonine355 (T355) is a major phosphorylation site of the CCR10 receptor. The pT355-CCR10 antibody detects phosphorylation in response to high- and low-efficacy agonists and after PKC activation. T355 phosphorylation is a key regulator...
$ 350.00 *
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NEW
Agonist-induced Threonine353 phosphorylation of the Chemokine Receptor 10
pT353-CCR10 (phospho-Chemokine Receptor 10...
Threonine353 (T353) is a major phosphorylation site of the CCR10 receptor. The pT353-CCR10 antibody detects phosphorylation in response to high- and low-efficacy agonists and after PKC activation. T353 phosphorylation is a key regulator...
$ 350.00 *
Details

CCR10

The CC chemokine receptor 10 (CCR10) is a receptor for two homeostatic chemokines: CCL27 and CCL28. CCR10 is one of the most important chemokine receptors in the mucosal immune system. CCR5 desensitization, β-arrestin recruitment and internalization are regulated by phosphorylation of carboxyl-terminal threonine353 (pT353-CCR10) and threonine355 (pT355-CCR10) residues. This nomenclature refers to the human CCR10. This phosphorylation motif is highly conserved across species and is also present in mice and rats. For more information on CCR10 pharmacology please refer to the IUPHAR database. For further reading refer to:

Bachelerie F, Ben-Baruch A, Burkhardt AM, Combadiere C, Farber JM, Graham GJ, Horuk R, Sparre-Ulrich AH, Locati M, Luster AD, Mantovani A, Matsushima K, Murphy PM, Nibbs R, Nomiyama H, Power CA, Proudfoot AE, Rosenkilde MM, Rot A, Sozzani S, Thelen M, Yoshie O, Zlotnik A. International Union of Basic and Clinical Pharmacology. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors. Pharmacol Rev. 2013 Nov 11;66(1):1-79. doi: 10.1124/pr.113.007724. Print 2014. Review. Erratum in: Pharmacol Rev. 2014 Apr;66(2):467. PubMed PMID: 24218476; PubMed Central PMCID: PMC3880466.

The CC chemokine receptor 10 (CCR10) is a receptor for two homeostatic chemokines: CCL27 and CCL28. CCR10 is one of the most important chemokine receptors in the mucosal immune system. CCR5... read more »
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CC Chemokine Receptor 10 Antibodies

CCR10

The CC chemokine receptor 10 (CCR10) is a receptor for two homeostatic chemokines: CCL27 and CCL28. CCR10 is one of the most important chemokine receptors in the mucosal immune system. CCR5 desensitization, β-arrestin recruitment and internalization are regulated by phosphorylation of carboxyl-terminal threonine353 (pT353-CCR10) and threonine355 (pT355-CCR10) residues. This nomenclature refers to the human CCR10. This phosphorylation motif is highly conserved across species and is also present in mice and rats. For more information on CCR10 pharmacology please refer to the IUPHAR database. For further reading refer to:

Bachelerie F, Ben-Baruch A, Burkhardt AM, Combadiere C, Farber JM, Graham GJ, Horuk R, Sparre-Ulrich AH, Locati M, Luster AD, Mantovani A, Matsushima K, Murphy PM, Nibbs R, Nomiyama H, Power CA, Proudfoot AE, Rosenkilde MM, Rot A, Sozzani S, Thelen M, Yoshie O, Zlotnik A. International Union of Basic and Clinical Pharmacology. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors. Pharmacol Rev. 2013 Nov 11;66(1):1-79. doi: 10.1124/pr.113.007724. Print 2014. Review. Erratum in: Pharmacol Rev. 2014 Apr;66(2):467. PubMed PMID: 24218476; PubMed Central PMCID: PMC3880466.

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