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Immuno-Grade µ-Opioid Receptor Antibodies

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KO-Validated
Immunohistochemical identification of µ-Opioid Receptor in caudate putamen.
MOP (IHC-grade), µ-Opioid Receptor Antibody
The µ-Opioid Receptor antibody is directed against the distal end of the carboxyl-terminal tail of mouse, rat and human MOP. It detects selectively the canonical form of MOP and none of the putative splice variants. In can be used to...
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The µ-opioid receptor (MOP) is the primary target for many potent analgesics used in the clinic including morphine, oxycodone, hydromorphone, fentanyl sufentanil and methadone. MOP is expressed on neuronal cell bodies and fibers in distinct regions of the central and peripheral nervous system. In the CNS, MOP is abundant in the cortex, amygdala, hippocampus, caudate-putamen, nucleus accumbens, thalamus, medial habenula, fasciculus retroflexus, interpeduncular nucleus, substantia nigra, superior and inferior colliculus, parabrachial nucleus, locus coeruleus, nucleus of the solitary tract, the superficial layers of the spinal cord dorsal horn as well as in the dorsal root ganglia (predominantly small- and medium-size cells). In the periphery, MOP is present in intramural ganglia of the gut and ganglion cells within the adrenal medulla.

The µ-opioid receptor (MOP) is the primary target for many potent analgesics used in the clinic including morphine, oxycodone, hydromorphone, fentanyl sufentanil and methadone. MOP is expressed on... read more »
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Immuno-Grade µ-Opioid Receptor Antibodies

The µ-opioid receptor (MOP) is the primary target for many potent analgesics used in the clinic including morphine, oxycodone, hydromorphone, fentanyl sufentanil and methadone. MOP is expressed on neuronal cell bodies and fibers in distinct regions of the central and peripheral nervous system. In the CNS, MOP is abundant in the cortex, amygdala, hippocampus, caudate-putamen, nucleus accumbens, thalamus, medial habenula, fasciculus retroflexus, interpeduncular nucleus, substantia nigra, superior and inferior colliculus, parabrachial nucleus, locus coeruleus, nucleus of the solitary tract, the superficial layers of the spinal cord dorsal horn as well as in the dorsal root ganglia (predominantly small- and medium-size cells). In the periphery, MOP is present in intramural ganglia of the gut and ganglion cells within the adrenal medulla.

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