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Neuropeptide Y Receptor 2 Antibodies

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Agonist-induced Serine369/Serine374 phosphorylation of the Neuropeptide Y receptor 2
pS369/pS374-NPY2 (phospho-Neuropeptide Y...
Serine369/Serine374 (S369/S374) is a major phosphorylation site of the Neuropeptide Y Receptor 2. The pS369/pS374-NPY2 antibody detects phosphorylation in response to high- and low-efficacy agonists but not after PKC activation....
$ 375.00 *
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NEW
Agonist-induced Serine354/Threonine356 phosphorylation of the Neuropeptide Y receptor 2
pS354/pT356-NPY2 (phospho-Neuropeptide Y...
Serine354Threonine356 (S354/T356) is a major phosphorylation site of the Neuropeptide Y Receptor 2. The pS354/pT356-NPY2 antibody detects phosphorylation in response to high- and low-efficacy agonists but not after PKC activation....
$ 375.00 *
Details
NEW
Agonist-induced Serine351/Serine354 phosphorylation of the Neuropeptide Y
pS351/pS354-NPY2 (phospho-Neuropeptide Y...
Serine351/Serine354 (S351/S354) is a major phosphorylation site of the Neuropeptide Y Receptor 2. The pS351/pS354-NPY2 antibody detects phosphorylation in response to high- and low-efficacy agonists but not after PKC activation....
$ 375.00 *
Details

NPY2

The NPY2 receptor can be found in CNS, intestine and heart. Signal transduction by the NPY2 receptor includes PTX-sensitive inhibition of cAMP production. BIIE0246 is a selective NPY2 receptor antagonist. NPY2 receptor desensitization and internalization are regulated by phosphorylation of carboxyl-terminal serine351/serine354 (pS351/pS354-NPY2), serine354/threonine356 (pS354/pT356-NPY2) and serine351/serine354 (pS369/pS374-NPY2). This nomenclature refers to the human NPY2 receptor. This phosphorylation motif is highly conserved across species and very similar in mice and humans. For more information on NPY2 pharmacology please refer to the IUPHAR database. For further reading refer to:

Beck-Sickinger, A., Colmers, W. F., Cox, H. M., Doods, H. N., Herzog, H., Larhammar, D., Michel, M. C., Quirion, R., Schwartz, T. and Westfall, T. (2019) “Neuropeptide Y receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database”, IUPHAR/BPS Guide to Pharmacology CITE, 2019(4). doi: 10.2218/gtopdb/F46/2019.4.

The NPY2 receptor can be found in CNS, intestine and heart. Signal transduction by the NPY2 receptor includes PTX-sensitive inhibition of cAMP production. BIIE0246 is a selective... read more »
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Neuropeptide Y Receptor 2 Antibodies

NPY2

The NPY2 receptor can be found in CNS, intestine and heart. Signal transduction by the NPY2 receptor includes PTX-sensitive inhibition of cAMP production. BIIE0246 is a selective NPY2 receptor antagonist. NPY2 receptor desensitization and internalization are regulated by phosphorylation of carboxyl-terminal serine351/serine354 (pS351/pS354-NPY2), serine354/threonine356 (pS354/pT356-NPY2) and serine351/serine354 (pS369/pS374-NPY2). This nomenclature refers to the human NPY2 receptor. This phosphorylation motif is highly conserved across species and very similar in mice and humans. For more information on NPY2 pharmacology please refer to the IUPHAR database. For further reading refer to:

Beck-Sickinger, A., Colmers, W. F., Cox, H. M., Doods, H. N., Herzog, H., Larhammar, D., Michel, M. C., Quirion, R., Schwartz, T. and Westfall, T. (2019) “Neuropeptide Y receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database”, IUPHAR/BPS Guide to Pharmacology CITE, 2019(4). doi: 10.2218/gtopdb/F46/2019.4.

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