Premium Phosphosite-Specific 7TM Antibodies
Novel Tools for Your GPCR Research
Select Your Country of Delivery below

GPR61 Receptor Antibodies

Close filters
No results were found for the filter!
NEW
Validation of the GPR61 Receptor in transfected HEK293 cells
GPR61 (non-phospho), G protein-coupled...
The non-phospho-GPR61 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR61. It can be used to detect total GPR61 receptors in Western blots independent of phosphorylation. The GPR61 antibody...
$ 375.00 *
Details

GPR61 is an orphan class-A G protein-coupled receptor. The endogenous ligand of GPR61 is still unknown. Mouse models of GPR61 disruption indicate a role for the receptor in regulation of appetite and body weight, indicating that the receptor may be a therapeutic target for obesity and eating disorders. GPR61 is primarily expressed in the central nervous system, particularly in the brain, including regions such as the cortex, hippocampus, and striatum. It is also found in immune cells, such as T lymphocytes and macrophages, indicating a potential role in immune modulation. While GPR61 is not yet a widely recognized pharmacological target, its expression in the CNS and immune cells suggests it may be involved in neurological disorders and inflammatory conditions. Research is ongoing to better understand its biological functions and identify potential ligands. For more information on GPR61 pharmacology please refer to the IUPHAR database. For further reading refer to:

Davenport AP, Alexander SP, Sharman JL, Pawson AJ, Benson HE, Monaghan AE, Liew WC, Mpamhanga CP, Bonner TI, Neubig RR, Pin JP, Spedding M, Harmar AJ. International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands. Pharmacol Rev. 2013 May 17;65(3):967-86. doi: 10.1124/pr.112.007179. PMID: 23686350; PMCID: PMC3698937.

Alexander SP, Battey J, Benson HE, Benya RV, Bonner TI, Davenport AP, Dhanachandra Singh K, Eguchi S, Harmar A, Holliday N, Jensen RT, Karnik S, Kostenis E, Liew WC, Monaghan AE, Mpamhanga C, Neubig R, Pawson AJ, Pin JP, Sharman JL, Spedding M, Spindel E, Stoddart L, Storjohann L, Thomas WG, Tirupula K, Vanderheyden P. Class A Orphans in GtoPdb v.2023.1. IUPHAR/BPS Guide to Pharmacology CITE. 2023; 2023(1). Available from: https://doi.org/10.2218/gtopdb/F16/2023.1.

GPR61 is an orphan class-A G protein-coupled receptor. The endogenous ligand of GPR61 is still unknown. Mouse models of GPR61 disruption indicate a role for the receptor in regulation of appetite... read more »
Close window
GPR61 Receptor Antibodies

GPR61 is an orphan class-A G protein-coupled receptor. The endogenous ligand of GPR61 is still unknown. Mouse models of GPR61 disruption indicate a role for the receptor in regulation of appetite and body weight, indicating that the receptor may be a therapeutic target for obesity and eating disorders. GPR61 is primarily expressed in the central nervous system, particularly in the brain, including regions such as the cortex, hippocampus, and striatum. It is also found in immune cells, such as T lymphocytes and macrophages, indicating a potential role in immune modulation. While GPR61 is not yet a widely recognized pharmacological target, its expression in the CNS and immune cells suggests it may be involved in neurological disorders and inflammatory conditions. Research is ongoing to better understand its biological functions and identify potential ligands. For more information on GPR61 pharmacology please refer to the IUPHAR database. For further reading refer to:

Davenport AP, Alexander SP, Sharman JL, Pawson AJ, Benson HE, Monaghan AE, Liew WC, Mpamhanga CP, Bonner TI, Neubig RR, Pin JP, Spedding M, Harmar AJ. International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands. Pharmacol Rev. 2013 May 17;65(3):967-86. doi: 10.1124/pr.112.007179. PMID: 23686350; PMCID: PMC3698937.

Alexander SP, Battey J, Benson HE, Benya RV, Bonner TI, Davenport AP, Dhanachandra Singh K, Eguchi S, Harmar A, Holliday N, Jensen RT, Karnik S, Kostenis E, Liew WC, Monaghan AE, Mpamhanga C, Neubig R, Pawson AJ, Pin JP, Sharman JL, Spedding M, Spindel E, Stoddart L, Storjohann L, Thomas WG, Tirupula K, Vanderheyden P. Class A Orphans in GtoPdb v.2023.1. IUPHAR/BPS Guide to Pharmacology CITE. 2023; 2023(1). Available from: https://doi.org/10.2218/gtopdb/F16/2023.1.

Recently viewed