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pS365/pT368-QRFPR (phospho-QRFP Receptor Antibody)

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Agonist-induced Serine365/Threonine368 phosphorylation of QRFP Receptor
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  • 7TM0333A
  • 100 µl
  • Rabbit
Serine365/Threonine368 (S365/T368) is a major phosphorylation site of the QRFP receptor.... more

Serine365/Threonine368 (S365/T368) is a major phosphorylation site of the QRFP receptor. The pS365/pT368-QRFPR antibody detects phosphorylation in response to high-efficacy agonists. S365/T368 phosphorylation is a key regulator of QRFPR desensitization, β-arrestin recruitment and internalization.

  Alternative Names GPR103 | G protein-coupled receptor... more

 

Alternative Names GPR103 | G protein-coupled receptor 103 | peptide p518 receptor
IUPHAR Target ID  333
UniProt ID Q96P65
Western Blot (WB)  1:1000
Immunocytochemistry (ICC)  -
Species Reactivity   Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Immunogen A synthetic phosphopeptide derived from human QRFPR around the phosphorylation site Ser365/Thr368.
Form  Liquid
Purification Antigen affinity chromatography
Storage buffer Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions short-term 4°C, long-term -20°C
Figure 1. Agonist-induced Serine365/Threonine368 phosphorylation of QRFP Receptor. Upper... more

Figure 1. Agonist-induced Serine365/Threonine368 phosphorylation of QRFP Receptor. Upper panel, HEK293 cells stably expressing the QRFP-Receptor (QRFPR) were either not exposed or exposed to 1 µM of specific QRFP-Receptor agonist QRFP26 for 30 minutes. Cells were lysed and immunoblotted with the anti-pS365/pT368-QRFPR antibody (7TM0333A) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with an phosphorylation-independent anti-QRFPR antibody to confirm equal loading of the gel.

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