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- Order number: 7TM0365A
- Content: 100 µl
- Host: Rabbit
Serine360/Serine361 (S360/S361) is major phosphorylation site of the Urotensin Receptor (UT). The pS360/pS361-UT antibody detects phosphorylation in response to agonists. S360/S361 phosphorylation is likely to be involved in efficient ligand sequestration by UT.
| Alternative Names | UT, UTR2, Urotensin Receptor, Urotensin 2 Receptor |
| IUPHAR Target ID | 365 |
| UniProt ID | Q9UKP6 |
| Western Blot (WB) | 1:1000 |
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Immunogen | A synthetic phosphopeptide derived from human UT around the phosphorylation site of Ser360/Ser361. |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage buffer | Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide |
| Storage conditions | short-term 4°C, long-term -20°C |
Figure 1. Agonist-induced Serine360/Serine361 phosphorylation of the Urotensin Receptor. Upper panel, HEK293 cells stably expressing the Urotensin receptor (UT) were either not exposed or exposed to 100 nM Urotensin-II for 30 minutes. Cells were lysed and immunoblotted with the anti-pS360/pS361-UT antibody (7TM0365A) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with the phosphorylation-independent anti-UT antibody (7TM0365N) to confirm equal loading of the gel.
Be the first to analyze the ACKR2 phosphorylation using our anti-pS348/pS350-ACKR2 antibody and let us know.



