pT372/pS373-B2 (phospho-Bradykinin Receptor 2 Antibody)

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Agonist-induced Threonine372/Serine373 phosphorylation of the Bradykinin Receptor 2

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Order number: 7TM0042B
Content: 100 µl
Host: Rabbit

Threonine372/Serine373 (T372/S373) is major phosphorylation site of the Bradykinin Receptor... more

Threonine372/Serine373 (T372/S373) is major phosphorylation site of the Bradykinin Receptor 2 (B2). The pT372/pS373-B2 antibody detects phosphorylation in response to agonists. T372/S373 phosphorylation is likely to be involved in efficient ligand sequestration by B2.

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Alternative Names B2BKR, BK-2 Receptor, Bradykinin Receptor 2 IUPHAR... more

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Alternative Names	B2BKR, BK-2 Receptor, Bradykinin Receptor 2
IUPHAR Target ID	42
UniProt ID	P30411
Western Blot (WB)	1:1000
Species Reactivity	Human
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Immunogen	A synthetic phosphopeptide derived from human B2 around the phosphorylation site of Thr372/Ser373.
Form	Liquid
Purification	Antigen affinity chromatography
Storage buffer	Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions	short-term 4°C, long-term -20°C

Figure 1. Agonist-induced Threonine372/Serine373 phosphorylation of the Bradykinin Receptor 2.... more

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Figure 1. Agonist-induced Threonine372/Serine373 phosphorylation of the Bradykinin Receptor 2. Upper panel, HEK293 cells stably expressing the Bradykinin receptor 2 (B2) were either not exposed or exposed to 100 nM Bradykinin for 30 minutes. Cells were lysed and immunoblotted with the anti-pT372/pS373-B2 antibody (7TM0042B) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with an phosphorylation-independent anti-B2 antibody to confirm equal loading of the gel.

Be the first to analyze the ACKR2 phosphorylation using our anti-pS348/pS350-ACKR2... more

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Be the first to analyze the ACKR2 phosphorylation using our anti-pS348/pS350-ACKR2 antibody and let us know.

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