Premium Phosphosite-Specific 7TM Antibodies
Your Resource for GPCR Research
Select Your Country of Delivery below

Complement Peptide Receptor Antibodies

Complement peptide receptors are activated by a small peptide fragments called C3a, C5a and C5adesArg (previously called anaphylatoxins) that are produced by the complement cascade. Complement peptides are potent chemoattractants and secretagogues that act on immune and non-immune cells. The physiological effects of complement peptides are mediated by a family of three seven transmembrane receptors (7TMRs) designated as C3a, C5a1 and C5a2. While C3a and C5a1 are classical G protein-coupled receptors (GPCRs), C5a2 appears to be permanently uncoupled from G proteins. However,  both C5a1 and C5a2 are required for full pro-inflammatory responses.

Close filters
2 From 2
No results were found for the filter!
NEW
Agonist-induced Threonine324/Serine327 phosphorylation of the Complement C5a Receptor 1.
pT324/pS327-C5a1 (phospho-Complement C5a...
Threonine324/serine327 (T324/S327) is a major phosphorylation site of the C5a1 receptor. The pT324/pS327-C5a1 antibody detects phosphorylation in response to high- and low-efficacy agonists but not after PKC activation. T324/S327...
$ 375.00 *
Details
2 From 2

For more information on complement peptide receptor pharmacology please refer to the IUPHAR database. For further reading refer to:

Klos A, Wende E, Wareham KJ, Monk PN. International Union of Basic and Clinical Pharmacology. [corrected]. LXXXVII. Complement peptide C5a, C4a, and C3a receptors. Pharmacol Rev. 2013 Jan;65(1):500-43. Review. Erratum in: Pharmacol Rev. 2014 Apr;66(2):466. PubMed PMID: 23383423.

For more information on complement peptide receptor pharmacology please refer to the IUPHAR database. For further reading refer to: Klos A, Wende E, Wareham KJ, Monk PN. International... read more »
Close window
Complement Peptide Receptor Antibodies

For more information on complement peptide receptor pharmacology please refer to the IUPHAR database. For further reading refer to:

Klos A, Wende E, Wareham KJ, Monk PN. International Union of Basic and Clinical Pharmacology. [corrected]. LXXXVII. Complement peptide C5a, C4a, and C3a receptors. Pharmacol Rev. 2013 Jan;65(1):500-43. Review. Erratum in: Pharmacol Rev. 2014 Apr;66(2):466. PubMed PMID: 23383423.

Recently viewed