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pS339/pS340-GAL2 (phospho-Galanin Receptor 2 Antibody)

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Agonist-induced Serine339/Serine340 phosphorylation of GAL2 Receptor
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  • 7TM0244C
  • 100 µl
  • Rabbit
Serine339/Serine340 (S339/S340) is a major phosphorylation site of the GAL2 receptor.... more

Serine339/Serine340 (S339/S340) is a major phosphorylation site of the GAL2 receptor. The pS339/pS340-GAL2 antibody detects phosphorylation in response to high-efficacy agonists. S339/S340 phosphorylation is a key regulator of GAL2 desensitization, β-arrestin recruitment and internalization.

  Alternative Names GALNR2, Galanin Receptor 2 IUPHAR Target ID... more

 

Alternative Names GALNR2, Galanin Receptor 2
IUPHAR Target ID  244
UniProt ID  O43603
Western Blot (WB)  1:1000
Immunocytochemistry (ICC)  -
Species Reactivity   Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Immunogen A synthetic phosphopeptide derived from human GAL2 around the phosphorylation site Ser339/Ser340.
Form  Liquid
Purification Antigen affinity chromatography
Storage buffer Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions short-term 4°C, long-term -20°C
Figure 1. Agonist-induced Serine339/Serine340 phosphorylation of GAL2 Receptor. Upper panel,... more

Figure 1. Agonist-induced Serine339/Serine340 phosphorylation of GAL2 Receptor. Upper panel, HEK293 cells stably expressing the GAL2-Receptor (GAL2) were either not exposed or exposed to 1 µM of specific GAL-Receptor agonist Galanin for 30 minutes. Cells were lysed and immunoblotted with the anti-pS339/pS340-GAL1 antibody (7TM0244C) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with an phosphorylation-independent anti-GAL2 antibody to confirm equal loading of the gel.

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