pS327/pS328-MRGPRX2 (phospho-MRGPRX2 Mas-related Receptor Antibody)

NEW

Agonist-induced Serine327/Serine328 phosphorylation of the MRGPRX2 Mas-related Receptor

$ 375.00 *

Ready to ship today,
Delivery time appr. 5-8 days

Order number: 7TM0157B
Content: 100 µl
Host: Rabbit

Serine327/Serine328 (S327/S329) is a major phosphorylation site of the MRGPRX2 Mas-related... more

Serine327/Serine328 (S327/S329) is a major phosphorylation site of the MRGPRX2 Mas-related receptor. The pS327/pS328-MRGPRX2 antibody detects phosphorylation in response to high- and low-efficacy agonists and after PKC activation. S327/S328 phosphorylation is a key regulator of MRGPRX2 desensitization, β-arrestin recruitment and internalization.

Available downloads:

Alternative Names MRGPRB 10, MRGX2 IUPHAR Target ID 157... more

Close menu

Alternative Names	MRGPRB 10, MRGX2
IUPHAR Target ID	157
UniProt ID	Q96LB1
Western Blot (WB)	1:1000
Immunocytochemistry (ICC)	-
Species Reactivity	Human
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Immunogen	A synthetic phosphopeptide derived from human MRGPRX2 around the phosphorylation site of Ser327/Ser328.
Form	Liquid
Purification	Antigen affinity chromatography
Storage buffer	Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions	short-term 4°C, long-term -20°C

Figure 1. Agonist-induced Serine327/Serine328 phosphorylation of the MRGPRX2 Mas-related... more

Close menu

Figure 1. Agonist-induced Serine327/Serine328 phosphorylation of the MRGPRX2 Mas-related Receptor. Upper panel, HEK293 cells stably expressing the MRGPRX2 Receptor (MRGPRX2) were either not exposed or exposed to 100 nM specific agonist ZINC-3573 for 30 minutes. Cells were lysed and immunoblotted with the anti-pS327/pS328-MRGPRX2 antibody (7TM0157B) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with an phosphorylation-independent anti-MRGPRX2 antibody to confirm equal loading of the gel.

Be the first to decipher the MRGPRX2 phosphorylation barcode and let us know. more

Close menu

Be the first to decipher the MRGPRX2 phosphorylation barcode and let us know.

Close menu