pS346/pS349/pT352-NPSR (phospho-NPS Receptor Antibody)

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Agonist-induced Serine346/Serine349/Threonine352 phosphorylation of the NPS Receptor

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Order number: 7TM0302A
Content: 100 µl
Host: Rabbit

Serine346/Serine349/threonine352 (S346/S349/T352) is major phosphorylation site of the NPS... more

Serine346/Serine349/threonine352 (S346/S349/T352) is major phosphorylation site of the NPS Receptor (NPSR). The pS346/pS349/pT352-NPRS antibody detects phosphorylation in response to agonists. S346/S349/T352 phosphorylation is likely to be involved in efficient ligand sequestration by NPSR.

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Alternative Names VRR1, Vasopressin Receptor-related Receptor IUPHAR... more

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Alternative Names	VRR1, Vasopressin Receptor-related Receptor
IUPHAR Target ID	302
UniProt ID	Q6W5P4
Western Blot (WB)	1:1000
Species Reactivity	Human
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Immunogen	A synthetic phosphopeptide derived from human NPSR around the phosphorylation site of Ser346/Ser349/Thr352.
Form	Liquid
Purification	Antigen affinity chromatography
Storage buffer	Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions	short-term 4°C, long-term -20°C

Figure 1. Agonist-induced Serine346/Serine349/Threonine352 phosphorylation of the NPS Receptor.... more

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Figure 1. Agonist-induced Serine346/Serine349/Threonine352 phosphorylation of the NPS Receptor. Upper panel, HEK293 cells stably expressing the NPS receptor (NPSR) were either not exposed or exposed to 100 nM Neuropeptide S for 30 minutes. Cells were lysed and immunoblotted with the anti-pS346/pS349/pT352-NPSR antibody (7TM0302A) at a dilution of 1:1000. Lower panels, blots were stripped and reprobed with the phosphorylation-independent anti-NPSR antibody (7TM0302N) to confirm equal loading of the gel.

Be the first to analyze the NPSR phosphorylation using our anti-pS346/pS349/pT352-NPSR... more

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Be the first to analyze the NPSR phosphorylation using our anti-pS346/pS349/pT352-NPSR antibody and let us know.

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