pS403/pS404-NTS1 (phospho-Neurotensin Receptor 1 Antibody)

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Agonist-induced Serine403/Serine404 phosphorylation of the Neurotensin Receptor 1

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Order number: 7TM0309B
Content: 100 µl
Host: Rabbit

Serine403/Serine404 (S403/S404) is major phosphorylation site of the Neurotensin Receptor 1... more

Serine403/Serine404 (S403/S404) is major phosphorylation site of the Neurotensin Receptor 1 (NTS1). The pS403/pS404-NTS1 antibody detects phosphorylation in response to agonists. S403/S404 phosphorylation is likely to be involved in efficient ligand sequestration by NTS1.

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Alternative Names NTS1, NTR1, Neurotensin Receptor Type 1, Neurotensin... more

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Alternative Names	NTS1, NTR1, Neurotensin Receptor Type 1, Neurotensin Receptor 1
IUPHAR Target ID	309
UniProt ID	P30989
Western Blot (WB)	1:1000
Species Reactivity	Human
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Immunogen	A synthetic phosphopeptide derived from human NTS1 around the phosphorylation site of Ser403/Ser404.
Form	Liquid
Purification	Antigen affinity chromatography
Storage buffer	Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions	short-term 4°C, long-term -20°C

Figure 1. Agonist-induced Serine403/Serine404 phosphorylation of the Neurotensin Receptor 1.... more

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Figure 1. Agonist-induced Serine403/Serine404 phosphorylation of the Neurotensin Receptor 1. Upper panel, HEK293 cells stably expressing the Neurotensin receptor 1 (NTS1) were either not exposed or exposed to 100 nM Neurotensin for 30 minutes. Cells were lysed and immunoblotted with the anti-pS403/pS404-NTS1 antibody (7TM0309B) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with the phosphorylation-independent anti-NTS1 antibody (7TM0309N) to confirm equal loading of the gel.

Be the first to analyze the ACKR2 phosphorylation using our anti-pS348/pS350-ACKR2... more

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Be the first to analyze the ACKR2 phosphorylation using our anti-pS348/pS350-ACKR2 antibody and let us know.

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