pS351/pT356-GPR17 (phospho-GPR17 Antibody)

NEW

$ 375.00 *

Ready to ship today,
Delivery time appr. 5-8 days

Order number: 7TM0088A
Content: 100 µl
Host: Rabbit

Serine351/Threonine356 (S351/T356) is a major phosphorylation site of the human GPR17 receptor.... more

Serine351/Threonine356 (S351/T356) is a major phosphorylation site of the human GPR17 receptor. The pS351/pT356-GPR17 antibody detects phosphorylation in response to high-efficacy agonists. S351/T356 phosphorylation is a key regulator of human GPR17 desensitization, β-arrestin recruitment and internalization.

Available downloads:

Alternative Names P2Y-like receptor, uracil nucleotide/cysteinyl... more

Close menu

Alternative Names	P2Y-like receptor, uracil nucleotide/cysteinyl leukotriene receptor
IUPHAR Target ID	88
UniProt ID	Q13304
Western Blot (WB)	1:1000
Immunocytochemistry (ICC)	-
Species Reactivity	Human
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Immunogen	A synthetic phosphopeptide derived from human GPR17 around the phosphorylation site Ser351/Thr356.
Form	Liquid
Purification	Antigen affinity chromatography
Storage buffer	Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions	short-term 4°C, long-term -20°C

Figure 1. Agonist-induced Serine351/Threonine356 phosphorylation of the G-protein coupled... more

Close menu

Figure 1. Agonist-induced Serine351/Threonine356 phosphorylation of the G-protein coupled Receptor 17. Upper panel, HEK293 cells stably expressing the G-protein coupled receptor 17 (GPR17) were either not exposed or exposed to 100 nM PSB-12150 for 30 minutes. Cells were lysed and immunoblotted with the anti-pS351/pT356-GPR17 antibody (7TM0088A) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with the phosphorylation-independent anti-GPR17 antibody (7TM0088N) to confirm equal loading of the gel.

Close menu

Read, write and discuss reviews... more

Close menu

Customer evaluation for "pS351/pT356-GPR17 (phospho-GPR17 Antibody)"

Write an evaluation

Evaluations will be activated after verification.