pS492/pS493-PTH1 (phospho-Parathyroid Hormone Receptor 1 Antibody)

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Agonist-induced Serine492/Serine493 phosphorylation of the Parathyroid Hormone Receptor 1

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Order number: 7TM0331C
Content: 100 µl
Host: Rabbit

Serine492/Serine493 (S492/S493) is major phosphorylation site of the Parathyroid Hormone... more

Serine492/Serine493 (S492/S493) is major phosphorylation site of the Parathyroid Hormone Receptor 1 (PTH1). The pS492/pS493-PTH1 antibody detects phosphorylation in response to agonists. S492/S493 phosphorylation is likely to be involved in efficient ligand sequestration by PTH1.

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Alternative Names PPR, PTHR IUPHAR Target ID 331... more

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Alternative Names	PPR, PTHR
IUPHAR Target ID	331
UniProt ID	Q03431
Western Blot (WB)	1:1000
Species Reactivity	Human
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Immunogen	A synthetic phosphopeptide derived from human PTH1 around the phosphorylation site of Ser492/Ser493.
Form	Liquid
Purification	Antigen affinity chromatography
Storage buffer	Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions	short-term 4°C, long-term -20°C

Figure 1. Agonist-induced Serine492/Serine493 phosphorylation of the Parathyroid Hormone... more

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Figure 1. Agonist-induced Serine492/Serine493 phosphorylation of the Parathyroid Hormone Receptor 1. Upper panel, HEK293 cells stably expressing the Prathyroid Hormone receptor 1 (PTH1) were either not exposed or exposed to 100 nM PTH for 30 minutes. Cells were lysed and immunoblotted with the anti-pS492/pS493-PTH1 antibody (7TM0331C) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with the phosphorylation-independent anti-PTH1 antibody (7TM0331N) to confirm equal loading of the gel.

Be the first to analyze the PTH1 phosphorylation using our anti-pS493/pS495-PTH1... more

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Be the first to analyze the PTH1 phosphorylation using our anti-pS493/pS495-PTH1 antibody and let us know.

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