pS338/pT342-ACKR4 (phospho-Atypical Chemokine Receptor 4 Antibody)

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Agonist-induced Serine338/Threonine342 phosphorylation of the Atypical Chemokine Receptor 4

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Order number: 7TM0315A
Content: 100 µl
Host: Rabbit

Serine338/Threonine342 (S338/T342) is major phosphorylation site of the Atypical Chemokine... more

Serine338/Threonine342 (S338/T342) is major phosphorylation site of the Atypical Chemokine Receptor 4 (ACKR4). The pS338/pT342-ACKR4 antibody detects phosphorylation in response to agonists. S338/ST42 phosphorylation is likely to be involved in efficient ligand sequestration by ACKR4.

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Alternative Names ACKR4, Atypical Chemokine Receptor 4 IUPHAR Target... more

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Alternative Names	ACKR4, Atypical Chemokine Receptor 4
IUPHAR Target ID	315
UniProt ID	Q9NPB9
Western Blot (WB)	1:1000
Species Reactivity	Human
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Immunogen	A synthetic phosphopeptide derived from human ACKR4 around the phosphorylation site of Ser338/Thr342.
Form	Liquid
Purification	Antigen affinity chromatography
Storage buffer	Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions	short-term 4°C, long-term -20°C

Figure 1. Agonist-induced Serine338/Threonine342 phosphorylation of the Atypical Chemokine... more

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Figure 1. Agonist-induced Serine338/Threonine342 phosphorylation of the Atypical Chemokine Receptor 4. Upper panel, HEK293 cells stably expressing the Atypical Chemokine receptor 4 (ACKR4) were either not exposed or exposed to 100 nM CCL-19 for 30 minutes. Cells were lysed and immunoblotted with the anti-pS338/pT342-ACKR4 antibody (7TM0315A) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with the phosphorylation-independent anti-ACKR4 antibody (7TM0315N-WB) to confirm equal loading of the gel.

Be the first to analyze the ACKR4 phosphorylation using our anti-pS338/pT342-ACKR4... more

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Be the first to analyze the ACKR4 phosphorylation using our anti-pS338/pT342-ACKR4 antibody and let us know.

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