pT344/pS345-DP2 (phospho-DP2 Prostanoid Receptor Antibody)

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Agonist-induced Threonine344/Serine345 phosphorylation of the Prostanoid Receptor 2

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Order number: 7TM0339B
Content: 100 µl
Host: Rabbit

Threonine344/Serine345 (T344/S345) is major phosphorylation site of the DP2 Prostanoid Receptor... more

Threonine344/Serine345 (T344/S345) is major phosphorylation site of the DP2 Prostanoid Receptor (DP2). The pT344/pS345-DP2 antibody detects phosphorylation in response to agonists. T344/S345 phosphorylation is likely to be involved in efficient ligand sequestration by DP2.

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Alternative Names Prostaglandin D2 Receptor 2, PGD2 Receptor IUPHAR... more

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Alternative Names	Prostaglandin D2 Receptor 2, PGD2 Receptor
IUPHAR Target ID	339
UniProt ID	Q9Y5Y4
Western Blot (WB)	1:1000
Species Reactivity	Human
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Immunogen	A synthetic phosphopeptide derived from human DP2 around the phosphorylation site of Thr344/Ser345.
Form	Liquid
Purification	Antigen affinity chromatography
Storage buffer	Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions	short-term 4°C, long-term -20°C

Figure 1. Agonist-induced Threon ine344/Serine345 phosphorylation of the Prostanoid Receptor... more

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Figure 1. Agonist-induced Threonine344/Serine345 phosphorylation of the Prostanoid Receptor 2. Upper panel, HEK293 cells stably expressing the Prostanoid receptor 2 (DP2) were either not exposed or exposed to 10 µM Treprostinil for 30 minutes. Cells were lysed and immunoblotted with the anti-pT344/pS345-DP2 antibody (7TM0339B) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with an phosphorylation-independent anti-DP2 antibody to confirm equal loading of the gel.

Be the first to analyze the DP2 phosphorylation using our anti-pT344/pS345-DP2... more

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Be the first to analyze the DP2 phosphorylation using our anti-pT344/pS345-DP2 antibody and let us know.

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