Prices plus VAT plus shipping costs
Ready to ship today,
Delivery time appr. 5-8 days
- Order number: 7TM0366A
- Content: 100 µl
- Host: Rabbit
Threonine378/Serine380 (T378/S380) is major phosphorylation site of the Vasopressin Receptor 1A (V1A). The pT378/pS380-V1A antibody detects phosphorylation in response to agonists. T378/S380 phosphorylation is likely to be involved in efficient ligand sequestration by V1A.
Alternative Names | AVPR1, V1aR, antidiuretic hormone receptor 1a |
IUPHAR Target ID | 366 |
UniProt ID | P37288 |
Western Blot (WB) | 1:1000 |
Species Reactivity | Human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Immunogen | A synthetic phosphopeptide derived from human V1A around the phosphorylation site of Thr378/Ser380. |
Form | Liquid |
Purification | Antigen affinity chromatography |
Storage buffer | Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide |
Storage conditions | short-term 4°C, long-term -20°C |
Figure 1. Agonist-induced Threonine378/Serine380 phosphorylation of the Vasopressin Receptor 1A. Upper panel, HEK293 cells stably expressing the Vasopressin receptor 1A (V1A) were either not exposed or exposed to 100 nM vasopressin for 30 minutes. Cells were lysed and immunoblotted with the anti-pT378/pS380-V1A antibody (7TM0366A) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with an phosphorylation-independent anti-V1A antibody to confirm equal loading of the gel.
Be the first to analyze the V2 phosphorylation using our anti-pT359/pT360-V2 antibody and let us know.