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pS338/pS339-DP2 (phospho-DP2 Prostanoid Receptor Antibody)

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pS338/pS339-DP2 (phospho-DP2 Prostanoid Receptor Antibody)
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  • 7TM0339A
  • 100 µl
  • Rabbit
Serine338/Serine339 (S338/S339) is major phosphorylation site of the DP2 Prostanoid Receptor... more

Serine338/Serine339 (S338/S339) is major phosphorylation site of the DP2 Prostanoid Receptor (DP2). The pS338/pS339-DP2 antibody detects phosphorylation in response to agonists. S338/S339 phosphorylation is likely to be involved in efficient ligand sequestration by DP2.

  Alternative Names Prostaglandin D2 Receptor 2, PGD2 Receptor IUPHAR... more

 

Alternative Names Prostaglandin D2 Receptor 2, PGD2 Receptor
IUPHAR Target ID  339
UniProt ID  Q9Y5Y4
Western Blot (WB)  1:1000
Species Reactivity   Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Immunogen A synthetic phosphopeptide derived from human DP2 around the phosphorylation site of Ser338/Ser339.
Form  Liquid
Purification Antigen affinity chromatography
Storage buffer Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions short-term 4°C, long-term -20°C
Figure 1. Agonist-induced Serine338/Serine339 phosphorylation of the Prostanoid Receptor 2.... more

Figure 1. Agonist-induced Serine338/Serine339 phosphorylation of the Prostanoid Receptor 2. Upper panel, HEK293 cells stably expressing the Prostanoid receptor 2 (DP2) were either not exposed or exposed to 10 µM Treprostinil for 30 minutes. Cells were lysed and immunoblotted with the anti-pS338/pS339-DP2 antibody (7TM0339A) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with an phosphorylation-independent anti-DP2 antibody to confirm equal loading of the gel.

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Be the first to analyze the DP2 phosphorylation using our anti-pS338/pS339-DP2 antibody and let us know.

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