pS377/pS378-OT (phospho-Oxytocin Receptor Antibody)

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Agonist-induced Serine377/Ser378 phosphorylation of the Oxytocin Receptor.

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Order number: 7TM0369B
Content: 100 µl
Host: Rabbit

Serine377/Serine378 (S377/S378) is major phosphorylation site of the Oxytocin Receptor ... more

Serine377/Serine378 (S377/S378) is major phosphorylation site of the Oxytocin Receptor (OT). The p3S77/pS378-OT antibody detects phosphorylation in response to agonists. S377/S378 phosphorylation is likely to be involved in efficient ligand sequestration.

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Alternative Names OTR IUPHAR Target ID 369... more

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Alternative Names	OTR
IUPHAR Target ID	369
UniProt ID	P30599
Western Blot (WB)	1:1000
Species Reactivity	Human
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Immunogen	A synthetic phosphopeptide derived from human OT around the phosphorylation site of Ser377/Ser378.
Form	Liquid
Purification	Antigen affinity chromatography
Storage buffer	Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions	short-term 4°C, long-term -20°C

Figure 1. Agonist-induced Serine377/Ser378 phosphorylation of the Oxytocin Receptor. Upper... more

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Figure 1. Agonist-induced Serine377/Ser378 phosphorylation of the Oxytocin Receptor. Upper panel, HEK293 cells stably expressing the Oxytocin receptor (OT) were either not exposed or exposed to 100 nM Vasopressin for 30 minutes. Cells were lysed and immunoblotted with the anti-pS377/pS378-OT antibody (7TM0369B) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with an phosphorylation-independent anti-OT antibody to confirm equal loading of the gel.

Be the first to analyze the V2 phosphorylation using our anti-pS350-V2 antibody and... more

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Be the first to analyze the V2 phosphorylation using our anti-pS350-V2 antibody and let us know.

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