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pT386/pS389-V1A (phospho-Vasopressin Receptor 1A Antibody)

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Agonist-induced Threonine386/Serine389 phosphorylation of the Vasopressin Receptor 1A
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  • 7TM0366B
  • 100 µl
  • Rabbit
Threonine386/Serine389 (T368/S389) is major phosphorylation site of the Vasopressin Receptor 1A... more

Threonine386/Serine389 (T368/S389) is major phosphorylation site of the Vasopressin Receptor 1A (V1A). The pT386/pS389-V1A antibody detects phosphorylation in response to agonists. T386/S389 phosphorylation is likely to be involved in efficient ligand sequestration by V1A.

  Alternative Names AVPR1, V1aR, antidiuretic hormone receptor 1a... more

 

Alternative Names AVPR1, V1aR, antidiuretic hormone receptor 1a
IUPHAR Target ID  366
UniProt ID   P37288
Western Blot (WB)  1:1000
Species Reactivity   Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Immunogen A synthetic phosphopeptide derived from human V1A around the phosphorylation site of Thr386/Ser389.
Form  Liquid
Purification Antigen affinity chromatography
Storage buffer Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions short-term 4°C, long-term -20°C
Figure 1. Agonist-induced Threonine386/Serine389 phosphorylation of the Vasopressin Receptor... more

Figure 1. Agonist-induced Threonine386/Serine389 phosphorylation of the Vasopressin Receptor 1A. Upper panel, HEK293 cells stably expressing the Vasopressin receptor 1A (V1A) were either not exposed or exposed to 100 nM vasopressin for 30 minutes. Cells were lysed and immunoblotted with the anti-pT386/pS389-V1A antibody (7TM0366B) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with an phosphorylation-independent anti-V1A antibody to confirm equal loading of the gel.

 

Be the first to analyze the V2 phosphorylation using our anti-pT359/pT360-V2... more

Be the first to analyze the V2 phosphorylation using our anti-pT359/pT360-V2 antibody and let us know.

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