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pS373/pS374-V1B (phospho-Vasopressin Receptor 1B Antibody)

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pS373/pS374-V1B (phospho-Vasopressin Receptor 1B Antibody)
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  • 7TM0367A
  • 100 µl
  • Rabbit
Serine373/Serine374 (S373/S374) is major phosphorylation site of the Vasopressin Receptor 1B... more

Serine373/Serine374 (S373/S374) is major phosphorylation site of the Vasopressin Receptor 1B (V1B). The pS373/pS374-V1B antibody detects phosphorylation in response to agonists. S373/S374 phosphorylation is likely to be involved in efficient ligand sequestration by V1B.

  Alternative Names AVPR3, V1bR, antidiuretic hormone receptor 1b,... more

 

Alternative Names AVPR3, V1bR, antidiuretic hormone receptor 1b, vasopressin V3 receptor
IUPHAR Target ID  367
UniProt ID  P47901
Western Blot (WB)  1:1000
Species Reactivity   Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Immunogen A synthetic phosphopeptide derived from human V1B around the phosphorylation site of Ser373/Ser374.
Form  Liquid
Purification Antigen affinity chromatography
Storage buffer Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions short-term 4°C, long-term -20°C
Figure 1. Agonist-induced Serine373/Serine374 phosphorylation of the Vasopressin Receptor 1B.... more

Figure 1. Agonist-induced Serine373/Serine374 phosphorylation of the Vasopressin Receptor 1B. Upper panel, HEK293 cells stably expressing the Vasopressin receptor 1B (V1B) were either not exposed or exposed to 100 nM vasopressin for 30 minutes. Cells were lysed and immunoblotted with the anti-pS373/pS374-V1B antibody (7TM0367A) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with an phosphorylation-independent anti-V1B antibody to confirm equal loading of the gel.

 

Be the first to analyze the V2 phosphorylation using our anti-pT359/pT360-V2... more

Be the first to analyze the V2 phosphorylation using our anti-pT359/pT360-V2 antibody and let us know.

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