pT338/pT340-CB2 (phospho-Cannabinoid Receptor 2 Antibody)

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Agonist-induced Threonine338/Threonine340 phosphorylation of the Cannabinoid Receptor 2

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Order number: 7TM0057B
Content: 100 µl
Host: Rabbit

Threonine338/Threonine340 (T338/T340) is major phosphorylation site of the Cannabinoid Receptor... more

Threonine338/Threonine340 (T338/T340) is major phosphorylation site of the Cannabinoid Receptor 2 (CB2). The pT338/pT340-CB2 antibody detects phosphorylation in response to agonists. T338/T340 phosphorylation is likely to be involved in efficient ligand sequestration by CB2.

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Alternative Names CB2-R, Peripheral Cannabinoid Receptor IUPHAR... more

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Alternative Names	CB2-R, Peripheral Cannabinoid Receptor
IUPHAR Target ID	57
UniProt ID	P34927
Western Blot (WB)	1:1000
Species Reactivity	Human
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Immunogen	A synthetic phosphopeptide derived from human CB2 around the phosphorylation site of Thr338/Thr340.
Form	Liquid
Purification	Antigen affinity chromatography
Storage buffer	Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions	short-term 4°C, long-term -20°C

Figure 1. Agonist-induced Threonine338/Threonine340 phosphorylation of the Cannabinoid Receptor... more

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Figure 1. Agonist-induced Threonine338/Threonine340 phosphorylation of the Cannabinoid Receptor 2. Upper panel, HEK293 cells stably expressing the CB2-Receptor (CB2) were either not exposed or exposed to 1 µM of CB2-Receptor agonists CP55940 or WIN55212-2 for 30 minutes. Cells were lysed and immunoblotted with the anti-pT338/pT340-CB2 antibody (7TM0057B) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with an phosphorylation-independent anti-CB2 antibody to confirm equal loading of the gel.

Be the first to analyze the CB2 phosphorylation using our anti-pT338/pT340-CB2... more

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Be the first to analyze the CB2 phosphorylation using our anti-pT338/pT340-CB2 antibody and let us know.

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