pT337/pS340-TP (phospho-TP Thromboxane Receptor Antibody)

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Agonist-induced Threonine337/Serine340 phosphorylation of the TP Thromboxane Receptor

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Order number: 7TM0346A
Content: 100 µl
Host: Rabbit

Threonine337/Serine340 (T337/S340) is major phosphorylation site of the TP Thromboxane Receptor... more

Threonine337/Serine340 (T337/S340) is major phosphorylation site of the TP Thromboxane Receptor (TP). The pT337/pS340-TP antibody detects phosphorylation in response to agonists. T337/S340 phosphorylation is likely to be involved in efficient ligand sequestration by TP.

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Alternative Names TXA2-R, Prostanoid TP Receptor IUPHAR Target ID... more

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Alternative Names	TXA2-R, Prostanoid TP Receptor
IUPHAR Target ID	346
UniProt ID	P21731
Western Blot (WB)	1:1000
Species Reactivity	Human
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Immunogen	A synthetic phosphopeptide derived from human TP around the phosphorylation site of Thr337/Ser340.
Form	Liquid
Purification	Antigen affinity chromatography
Storage buffer	Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions	short-term 4°C, long-term -20°C

Figure 1. Agonist-induced Threonine337/Serine340 phosphorylation of the TP Thromboxane... more

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Figure 1. Agonist-induced Threonine337/Serine340 phosphorylation of the TP Thromboxane Receptor. Upper panel, HEK293 cells stably expressing the TP Thromboxane receptor (TP) were either not exposed or exposed to 10 µM U46619for 30 minutes. Cells were lysed and immunoblotted with the anti-pT337/pS340-TP antibody (7TM0346A) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with an phosphorylation-independent anti-TP antibody to confirm equal loading of the gel.

Be the first to analyze the TP phosphorylation using our anti-pT337/pS340-TP... more

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Be the first to analyze the TP phosphorylation using our anti-pT337/pS340-TP antibody and let us know.

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