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pS377/pS378-OT (phospho-Oxytocin Receptor Antibody)

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Agonist-induced Serine377/Ser378 phosphorylation of the Oxytocin Receptor.
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  • 7TM0369B
  • 100 µl
  • Rabbit
Serine377/Serine378 (S377/S378) is major phosphorylation site of the Oxytocin Receptor ... more

Serine377/Serine378 (S377/S378) is major phosphorylation site of the Oxytocin Receptor  (OT). The p3S77/pS378-OT antibody detects phosphorylation in response to agonists. S377/S378 phosphorylation is likely to be involved in efficient ligand sequestration.

  Alternative Names OTR IUPHAR Target ID   369... more

 

Alternative Names OTR
IUPHAR Target ID  369
UniProt ID  P30599
Western Blot (WB)  1:1000
Species Reactivity   Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Immunogen A synthetic phosphopeptide derived from human OT around the phosphorylation site of Ser377/Ser378.
Form  Liquid
Purification Antigen affinity chromatography
Storage buffer Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions short-term 4°C, long-term -20°C
Figure 1. Agonist-induced Serine377/Ser378 phosphorylation of the Oxytocin Receptor. Upper... more

Figure 1. Agonist-induced Serine377/Ser378 phosphorylation of the Oxytocin Receptor. Upper panel, HEK293 cells stably expressing the Oxytocin receptor (OT) were either not exposed or exposed to 100 nM Vasopressin for 30 minutes. Cells were lysed and immunoblotted with the anti-pS377/pS378-OT antibody (7TM0369B) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with an phosphorylation-independent anti-OT antibody to confirm equal loading of the gel.

 

Be the first to analyze the V2 phosphorylation using our anti-pS350-V2 antibody  and... more

Be the first to analyze the V2 phosphorylation using our anti-pS350-V2 antibody and let us know.

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