pS397/pT398-V1A (phospho-Vasopressin Receptor 1A Antibody)

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Agonist-induced Serine397/Threonine398 phosphorylation of the Vasopressin Receptor 1A

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Order number: 7TM0366C
Content: 100 µl
Host: Rabbit

Serine397/Threonine398 (S397/T398) is major phosphorylation site of the Vasopressin Receptor 1A... more

Serine397/Threonine398 (S397/T398) is major phosphorylation site of the Vasopressin Receptor 1A (V1A). The pS397/pT398-V1A antibody detects phosphorylation in response to agonists. S397/T398 phosphorylation is likely to be involved in efficient ligand sequestration by V1A.

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Alternative Names AVPR1, V1aR, antidiuretic hormone receptor 1a... more

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Alternative Names	AVPR1, V1aR, antidiuretic hormone receptor 1a
IUPHAR Target ID	366
UniProt ID	P37288
Western Blot (WB)	1:1000
Species Reactivity	Human
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Immunogen	A synthetic phosphopeptide derived from human V1A around the phosphorylation site of Ser397/Thr398.
Form	Liquid
Purification	Antigen affinity chromatography
Storage buffer	Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions	short-term 4°C, long-term -20°C

Figure 1. Agonist-induced Serine397/Threonine398 phosphorylation of the Vasopressin Receptor... more

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Figure 1. Agonist-induced Serine397/Threonine398 phosphorylation of the Vasopressin Receptor 1A. Upper panel, HEK293 cells stably expressing the Vasopressin receptor 1A (V1A) were either not exposed or exposed to 100 nM vasopressin for 30 minutes. Cells were lysed and immunoblotted with the anti-pS397/pT398-V1A antibody (7TM0366C) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with an phosphorylation-independent anti-V1A antibody to confirm equal loading of the gel.

Be the first to analyze the V2 phosphorylation using our anti-pT359/pT360-V2... more

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Be the first to analyze the V2 phosphorylation using our anti-pT359/pT360-V2 antibody and let us know.

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