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pS350-V2 (phospho-Vasopressin Receptor 2 Antibody)

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Agonist-induced Serine350 phosphorylation of the Vasopressin Receptor 2
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  • 7TM0368A
  • 100 µl
  • Rabbit
Serine350 (S350) is major phosphorylation site of the Vasopresssin Receptor 2 (V2). The pS350-V2... more

Serine350 (S350) is major phosphorylation site of the Vasopresssin Receptor 2 (V2). The pS350-V2 antibody detects phosphorylation in response to agonists. S350 phosphorylation is likely to be involved in efficient ligand sequestration by V2.

  Alternative Names ADHR, DIR3, renal-type arginine vasopressin receptor... more

 

Alternative Names ADHR, DIR3, renal-type arginine vasopressin receptor
IUPHAR Target ID  368
UniProt ID  P30518
Western Blot (WB)  1:1000
Species Reactivity   Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Immunogen A synthetic phosphopeptide derived from human V2 around the phosphorylation site of Ser350.
Form  Liquid
Purification Antigen affinity chromatography
Storage buffer Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions short-term 4°C, long-term -20°C
Figure 1. Agonist-induced Serine350 phosphorylation of the Vasopressin Receptor 2. Upper... more

Figure 1. Agonist-induced Serine350 phosphorylation of the Vasopressin Receptor 2. Upper panel, HEK293 cells stably expressing the Vasopressin receptor 2 (V2) were either not exposed or exposed to 100 nM Vasopressin for 30 minutes. Cells were lysed and immunoblotted with the anti-pS350-V2 antibody (7TM0368A) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with an phosphorylation-independent anti-V2 antibody to confirm equal loading of the gel.

 

Be the first to analyze the V2 phosphorylation using our anti-pS350-V2 antibody  and... more

Be the first to analyze the V2 phosphorylation using our anti-pS350-V2 antibody and let us know.

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