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pT338/pT340-CB2 (phospho-Cannabinoid Receptor 2 Antibody)

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Agonist-induced Threonine338/Threonine340 phosphorylation of the Cannabinoid Receptor 2
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  • 7TM0057B
  • 100 µl
  • Rabbit
Threonine338/Threonine340 (T338/T340) is major phosphorylation site of the Cannabinoid Receptor... more

Threonine338/Threonine340 (T338/T340) is major phosphorylation site of the Cannabinoid Receptor 2 (CB2). The pT338/pT340-CB2 antibody detects phosphorylation in response to agonists. T338/T340 phosphorylation is likely to be involved in efficient ligand sequestration by CB2.

  Alternative Names CB2-R, Peripheral Cannabinoid Receptor IUPHAR... more

 

Alternative Names CB2-R, Peripheral Cannabinoid Receptor
IUPHAR Target ID  57
UniProt ID  P34927
Western Blot (WB)  1:1000
Species Reactivity   Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Immunogen A synthetic phosphopeptide derived from human CB2 around the phosphorylation site of Thr338/Thr340.
Form  Liquid
Purification Antigen affinity chromatography
Storage buffer Dulbecco's PBS, pH 7.4, with 150 mM NaCl, 0.02% sodium azide
Storage conditions short-term 4°C, long-term -20°C
Figure 1. Agonist-induced Threonine338/Threonine340 phosphorylation of the Cannabinoid Receptor... more

Figure 1. Agonist-induced Threonine338/Threonine340 phosphorylation of the Cannabinoid Receptor 2. Upper panel, HEK293 cells stably expressing the CB2-Receptor (CB2) were either not exposed or exposed to 1 µM of CB2-Receptor agonists CP55940 or WIN55212-2 for 30 minutes. Cells were lysed and immunoblotted with the anti-pT338/pT340-CB2 antibody (7TM0057B) at a dilution of 1:1000. Lower panel, blot was stripped and reprobed with an phosphorylation-independent anti-CB2 antibody to confirm equal loading of the gel.

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Be the first to analyze the CB2 phosphorylation using our anti-pT338/pT340-CB2 antibody and let us know.

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